![]() ![]() Following a successful collegiate career at Nichols College (NCAA III) in 2015, the Ambler, Pennsylvania native joined the Icemen for 11 games when the franchise was located in Evansville. Before joining the Icemen, the 6-foot, 194-pound defenseman played 12 games in France for Brest where he was plus-10 with four points (1G, 3A). Kyle Shapiro, 28, played 24 games for the Icemen last season with three points (1G, 2A) and a plus-5 rating. The interviews listed here are drawn from longer interviews that can be accessed at the National Library of Australia, Canberra, and the State Library of Victoria, Melbourne.Jacksonville, FL– The Jacksonville Icemen, proud affiliate of the NHL Winnipeg Jets and AHL Manitoba Moose, today announced the addition of defensemen Kyle Shapiro, Spencer Metcalfe, and Blake Kessel to the 2018-2019 training camp roster. Don Metcalf: cancer researcher at the Walter and Eliza Hall Institute (4:08).Searching for the answers at Sydney University (7:27).In 2005 Professor Metcalf was interviewed for the WEHI Revisited series (produced by Louise Darmody, Sound Memories), in which several Institute luminaries spoke about what drove them to pursue a career in medical research, and shared memories of life at the Institute. He was named an Officer of the Order of Australia (AO) in 1976 and a Companion of the Order (AC) in 1993.Īlbert Lasker Award for Clinical Medical ResearchĢ007 American Association for Cancer Research Lifetime Achievement Awardġ994 Gairdner Foundation International Awardġ993 Albert Lasker Award for Clinical Medical Researchġ989 Alfred P Sloan Prize of the General Motors Cancer Research Foundationġ988 Foreign Associate of the US National Academy of Sciencesġ987 Bristol-Myer Prize for Distinguished Cancer Researchġ983 Fellow of the Royal Society of Londonġ969 Fellow of the Australian Academy of Science Don Metcalf interviews Professor Metcalf’s work was honoured through his election to scientific academies in Australia, the UK and the US and by the awarding of almost every major international science prize. He also attended Professor Metcalf’s seventieth birthday in 1997 to sing him Happy Birthday. Señor Carreras visited the Institute in 1991 to meet Professor Metcalf and thank him for his role in developing the treatment. ![]() One of the first patients to benefit from Professor Metcalf’s work was famed Spanish tenor, Señor Jose Carreras.ĬSF recipient Señor Jose Carreras (L) meetsĪfter being diagnosed with acute myeloid leukaemia, which did not respond to initial treatment, Señor Carreras received a treatment regime that included CSF therapy in 1987. In his last months, with poor health finally preventing him from coming into the Institute, he requested a microscope be set up at home so he could continue working as long as possible. To date, Professor Metcalf’s discovery has benefited more than 20 million cancer patients worldwide.ĬSFs also revolutionised transplant medicine, leading to new techniques for performing bone marrow transplants for patients with blood diseases such as leukaemia.Īlthough officially retiring in1996, Professor Metcalf continued his research at the Institute for a further 18 years, studying the regulation of normal and leukaemic blood cells. These were dubbed ‘colony stimulating factors’, or CSFs, because they stimulated the production of white blood cells.īy the late 1980s gene cloning enabled mass production of CSFs, and they were rolled out to clinics worldwide. Over a period of fifteen years Metcalf and his colleagues identified and purified four hormones that regulate blood cell production. These white blood cells become severely depleted in cancer patients undergoing chemotherapy, leaving them vulnerable to serious and sometimes fatal infections. In the early 1960s Professor Metcalf speculated that there must be a biological mechanism – one or more hormones – that controlled white blood cell production. ![]() ![]() In 1966, Professor Metcalf became deputy director of the Institute, under newly appointed director Sir Gustav Nossal. He undertook postdoctoral work at Harvard Medical School from 1956 to 1958, before returning to the Institute as head of the Cancer Research laboratory. He spent his early years here studying vaccinia virus under Sir Frank Macfarlane Burnet. Professor Metcalf began his research at the Walter and Eliza Hall Institute in 1954 with a Carden Fellowship in cancer research from the Anti-Cancer Council of Victoria (now Cancer Council Victoria). He is best known for his pioneering discovery of colony stimulating factors, which have helped more than 20 million people worldwide. Professor Don Metcalf is regarded as the ‘father of modern haematology’. ![]()
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